What is Autism Spectrum Disorder?
Autism spectrum disorder (ASD) is a developmental disorder, often manifested in early childhood, characterized by impaired communication and social interactions, and repetitive and/or restrictive behaviors. Autism is one of the most frequent childhood disorders affecting approximately 1 in 68 children, with boys affected almost five times more frequently than girls.
The Genetics of Autism
Genetics have been shown to have a prominent role in the development of autism spectrum disorder. Numerous studies have shown that autism has a strong genetic component with most estimating heritability from 70 to 90%. In the vast majority of cases, autism seems to be a multi-gene disease, involving variations of several genes in variable proportions and locations.
The ARISk Test
The ARISk Test is a genetic test designed to identify the risk of autism spectrum disorder (ASD) in children who have signs of developmental delay, a clinical suspicion of autism, or an older sibling previously diagnosed with an ASD.
IntegraGen researchers have published numerous peer-reviewed papers based on the genetics of autism and the ARISk Test. These studies have provide scientific evidence on the role of single nucleotide polymorphisms (SNPs) in autism spectrum disorder.